What is the maximum total amiodarone dose in mg/kg for pediatric arrest?

What is the maximum total amiodarone dose in mg/kg for pediatric arrest?

• A. 15 mg/kg
• B. 10 mg/kg
• C. 20 mg/kg
• D. 5 mg/kg

Answer: (A)

In pediatric arrest, amiodarone is used as an antiarrhythmic for shock-refractory VT/VF after defibrillation and epinephrine. The dosing is weight-based: you give 5 mg/kg IV/IO as a bolus, and you may repeat it. The total amount given across the arrest should not exceed 15 mg/kg. So the maximum total amiodarone dose for a pediatric arrest is 15 mg/kg. This limit helps balance the antiarrhythmic benefit with the risk of toxicity, especially since amiodarone can affect blood pressure and has a long potential half-life.

In pediatric arrest, amiodarone is used as an antiarrhythmic for shock-refractory VT/VF after defibrillation and epinephrine. The dosing is weight-based: you give 5 mg/kg IV/IO as a bolus, and you may repeat it. The total amount given across the arrest should not exceed 15 mg/kg. So the maximum total amiodarone dose for a pediatric arrest is 15 mg/kg. This limit helps balance the antiarrhythmic benefit with the risk of toxicity, especially since amiodarone can affect blood pressure and has a long potential half-life.